Combinations ; - see below
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Artesun | Guilin Pharmaceuticals Ltd. | Pharma Specialities Ltd. | 30mg | 5 | Injection | per vial | KES 742.00 |
| Artesun | Guilin Pharmaceuticals Ltd. | Pharma Specialities Ltd. | 60mg | 5 | Injection | per vial | KES 1,158.00 |
| Artesun | Guilin Pharmaceuticals Ltd. | Pharma Specialities Ltd. | 120mg | 5 | Injection | per vial | KES 1,852.00 |
| Falcinat | Dawa Limited | Dawa Limited | 100mg | 6 | Tablet | per tablet | KES 180.00 |
| Falcinil | Cipla Ltd. | Surgipharm Ltd | 100mg | 6 | Tablet | per tablet | KES 240.00 |
| Falcinil | Cipla Ltd. | Surgipharm Ltd | 60mg | 1 | Injection | per vial | KES 315.00 |
| Esunate | Elys Chemicals Industries Ltd. | Elys Chemical Industries Ltd. | 100mg | 6 | Tablet | per tablet | KES 60.00 |
| Larinate | IPCA | Sai Pharmaceuticals Ltd. | 60mg | 1 | Injection | per vial | KES 180.00 |
| Resunate | Regal Pharmaceuticals | Regal Pharmaceuticals Limited | 50mg | 12 | Tablet | per tablet | KES 224.00 |
| Zysunate | Zydus Cadila Healthcare | Harley's Limited | 50mg | 12 | Tablet | per tablet | KES 231.00 |
| Artesunate sodium More info | |
|---|---|
| Mode Of Action | Artemisinin derivatives are concentrated in the parasitized erythrocytes and it is believed that iron from ingested haemoglobin of the parasite?s victim reduces ?endoperoxide bridge? releasing a highly reactive free radical iron (IV) oxo species that rips apart the parasitic cells. |
| Drug Indication | Falciparum malaria, resistant malaria. |
| Side Effects | Minimal - rarely transient abdominal pain, diarrhoea and tinnitus |
| Dosage | 2.4 mg/kg body weight IV or IM given on admission (time = 0), then at 12 h and 24 h, then once a day. |
| Special Information | Artesunate reconstituition: Step 1: The powder for injection should be reconstituted with 1mL of 5% sodium bicarbonate and shaken vigorously till the solution becomes clear. Step 2: For I.V. use, add 5 mL (2mL for I.M. use) of normal saline or 5% of glucose and mix again. Step 3: For I.V. use, the required amount of the drug is administered slowly over a period of 2 - 3 minutes. The powder for injection is difficult to dissolve and care should be taken to ensure that it is completely dissolved before parenteral administration. It should always be used immediately after reconstitution. If the solution is cloudy or a precipitate is present, the parenteral preparation should be discarded. |
| Pregnancy Category | Category B: |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Categorized further into: |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Anti-Malarials |